This is a compound discovered in the sap of the guggul tree, which grows in Asia (India, Pakistan, and Afghanistan) where it has been used for two thousand years to control weight and treat arthritis. Guggulsterones seems to have thyroid-stimulating properties and to assist with the conversion of T4 (inactive thyroid hormone) to Thyroxyl T3 (an active thyroid hormone). In this way it increases metabolic rate and help the weight loss process. Various studies have also found that guggulsterone helps advance the ratio of HDL to LDL by increasing the good cholesterol and lowering the bad cholesterol. Many have used this product as a fat burner and had decent results while using it.